Enhanced Pedigree Error Detection

  title={Enhanced Pedigree Error Detection},
  author={L. Sun and K. Wilder and M. S. McPeek},
  journal={Human Heredity},
  pages={110 - 99}
  • L. Sun, K. Wilder, M. S. McPeek
  • Published 2002
  • Computer Science, Medicine
  • Human Heredity
  • Accurate information on the relationships among individuals in a study is critical for valid linkage analysis. We extend the MLLR, EIBD, AIBS and IBS tests for detection of misspecified relationships to a broader range of relative pairs, and we improve the two-stage screening procedure for analyzing large data sets. We have developed software, PREST, which calculates the test statistics and performs the corresponding hypothesis tests for relationship misclassification in general outbred… CONTINUE READING
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