Enhanced Oral Bioavailability and Improved Biological Activities of a Quercetin/Resveratrol Combination Using a Liquid Self-Microemulsifying Drug Delivery System.

@article{Jaisamut2020EnhancedOB,
  title={Enhanced Oral Bioavailability and Improved Biological Activities of a Quercetin/Resveratrol Combination Using a Liquid Self-Microemulsifying Drug Delivery System.},
  author={Patcharawalai Jaisamut and Subhaphorn Wanna and Surasak Limsuwan and Sasitorn Chusri and Kamonthip Wiwattanawongsa and Ruedeekorn Wiwattanapatapee},
  journal={Planta medica},
  year={2020}
}
Both quercetin and resveratrol are promising plant-derived compounds with various well-described biological activities; however, they are categorized as having low aqueous solubility and labile natural compounds. The purpose of the present study was to propose a drug delivery system to enhance the oral bioavailability of combined quercetin and resveratrol. The suitable self-microemulsifying formulation containing quercetin together with resveratrol comprised 100 mg Capryol 90, 700 mg Cremophor… 
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