Enhanced Nucleophilic Fluorination and Radiofluorination of Organosilanes Appended with Potassium-Chelating Leaving Groups.

@article{Alhuniti2014EnhancedNF,
  title={Enhanced Nucleophilic Fluorination and Radiofluorination of Organosilanes Appended with Potassium-Chelating Leaving Groups.},
  author={Mohammed H. Al-huniti and Shuiyu Lu and Victor W. Pike and Salvatore D Lepore},
  journal={Journal of fluorine chemistry},
  year={2014},
  volume={158},
  pages={48-52}
}
Here we aimed to explore the feasibility of enhancing the fluorination of organosilanes by appending potassium-chelating groups to the substrates. For this purpose, eight organosilanes were prepared in which a linear or cyclic leaving group, with putative potassium-chelating ability, was attached covalently to a congested silicon atom via an ether linkage… CONTINUE READING