Corpus ID: 23717789

Enhanced GFR response to oral versus intravenous arginine administration in normal adults.

@article{Smoyer1991EnhancedGR,
  title={Enhanced GFR response to oral versus intravenous arginine administration in normal adults.},
  author={W. Smoyer and B. Brouhard and D. Rassin and L. Lagrone},
  journal={The Journal of laboratory and clinical medicine},
  year={1991},
  volume={118 2},
  pages={
          166-75
        }
}
Both oral protein ingestion and intravenous amino acid infusions have been shown to increase glomerular filtration rate (GFR) and renal plasma flow (RPF) in normal subjects. Although the mechanism of this effect is not known, the renal responses to these loads have been associated with increases in peripheral glucagon concentrations. Conflicting data exist concerning the role of glucagon in the hyperfiltration response after an oral protein meal or administration of an intravenous amino acid… Expand
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References

Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbit.
TLDR
This is the first study to demonstrate that supplementation of dietary L-arginine, the EDRF precursor, improves endothelium-dependent vasorelaxation and is associated with a reduction in atherogenesis. Expand