Enhanced CXCL1 production and angiogenesis in adenosine-mediated lung disease.

  title={Enhanced CXCL1 production and angiogenesis in adenosine-mediated lung disease.},
  author={Amir Mohsenin and Marie D. Burdick and Jos{\'e} Granero Molina and Michael P. Keane and Michael R. Blackburn},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={21 4},
Angiogenesis is a feature of chronic lung diseases such as asthma and pulmonary fibrosis; however, the pathways controlling pathological angiogenesis during lung disease are not completely understood. Adenosine is a signaling molecule that has been implicated in the exacerbation of chronic lung disease and in the regulation of angiogenesis; however, the relationship between these factors has not been investigated. The current study utilized adenosine deaminase (ADA)-deficient mice to determine… CONTINUE READING


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