Engrailed, Wnt and Pax genes regulate midbrain--hindbrain development.

@article{Joyner1996EngrailedWA,
  title={Engrailed, Wnt and Pax genes regulate midbrain--hindbrain development.},
  author={Alexandra L. Joyner},
  journal={Trends in genetics : TIG},
  year={1996},
  volume={12 1},
  pages={
          15-20
        }
}
  • A. Joyner
  • Published 1996
  • Biology, Medicine
  • Trends in genetics : TIG
The mouse Engrailed, Wnt and Pax genes, which are homologues of Drosophila segmentation genes, have provided a critical genetic entry point for dissecting the molecular and cellular control of mesencephalon and metencephalon development in vertebrates. Mutant phenotypes and gene expression data suggest that six members of these gene families are required for early formation of these brain regions. Ectopic transplantation studies have shown that the midbrain-hindbrain-junction protein can act as… Expand
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TLDR
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