Engraftment of mesenchymal stem cells into dystrophin-deficient mice is not accompanied by functional recovery.

@article{Gang2009EngraftmentOM,
  title={Engraftment of mesenchymal stem cells into dystrophin-deficient mice is not accompanied by functional recovery.},
  author={Eun Ji Gang and Radbod Darabi and Darko Bosnakovski and Zhaohui Xu and Kristine E. Kamm and Michael Kyba and Rita C R Perlingeiro},
  journal={Experimental cell research},
  year={2009},
  volume={315 15},
  pages={2624-36}
}
Mesenchymal stem cell preparations have been proposed for muscle regeneration in musculoskeletal disorders. Although MSCs have great in vitro expansion potential and possess the ability to differentiate into several mesenchymal lineages, myogenesis has proven to be much more difficult to induce. We have recently demonstrated that Pax3, the master regulator of the embryonic myogenic program, enables the in vitro differentiation of a murine mesenchymal stem cell line (MSCB9-Pax3) into myogenic… CONTINUE READING

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