Engraftment of human peripheral blood lymphocytes in normal strains of mice.

  title={Engraftment of human peripheral blood lymphocytes in normal strains of mice.},
  author={Ido Lubin and Harry Segall and Hadar Marcus and Muriel David and L Kulova and Michael Steinitz and Porat Erlich and Judith Gan and Yair Reisner},
  volume={83 8},
Transplantation of bone marrow from SCID mice into lethally irradiated normal mice can potentially endow the normal recipients with characteristics typical of the immune-deficient SCID mouse. In the present study, we investigated whether intraperitoneal grafting of human peripheral blood lymphocytes (PBLs), which has been documented in the SCID mouse, can also be achieved in irradiated BALB/c mice radioprotected with SCID bone marrow. Evaluation of different radiation protocols suggested that… CONTINUE READING


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