# Engineering stability in gene networks by autoregulation

@article{Becskei2000EngineeringSI,
title={Engineering stability in gene networks by autoregulation},
author={Attila Becskei and Luis Serrano},
journal={Nature},
year={2000},
volume={405},
pages={590-593}
}
• Published 1 June 2000
• Biology, Medicine
• Nature
The genetic and biochemical networks which underlie such things as homeostasis in metabolism and the developmental programs of living cells, must withstand considerable variations and random perturbations of biochemical parameters. These occur as transient changes in, for example, transcription, translation, and RNA and protein degradation. The intensity and duration of these perturbations differ between cells in a population. The unique state of cells, and thus the diversity in a population…
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