Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast.

@article{Skjoedt2016EngineeringPT,
  title={Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast.},
  author={Mette L Skjoedt and Tim Snoek and Kanchana R Kildegaard and Dushica Arsovska and Michael Eichenberger and Tobias J Goedecke and Arun Stephen Rajkumar and Jie Zhang and Mette Kristensen and Beata Joanna Lehka and Solvej Siedler and Irina Borodina and Michael K Jensen and Jay D Keasling},
  journal={Nature chemical biology},
  year={2016},
  volume={12 11},
  pages={951-958}
}
Whole-cell biocatalysts have proven a tractable path toward sustainable production of bulk and fine chemicals. Yet the screening of libraries of cellular designs to identify best-performing biocatalysts is most often a low-throughput endeavor. For this reason, the development of biosensors enabling real-time monitoring of production has attracted attention… CONTINUE READING