Engineering of nano-crystalline drug suspensions: employing a physico-chemistry based stabilizer selection methodology or approach.

@article{Nakach2014EngineeringON,
  title={Engineering of nano-crystalline drug suspensions: employing a physico-chemistry based stabilizer selection methodology or approach.},
  author={Mostafa Nakach and Jean-Ren{\'e} Authelin and Tharwat F. Tadros and Laurence Galet and Alain Chamayou},
  journal={International journal of pharmaceutics},
  year={2014},
  volume={476 1-2},
  pages={277-88}
}
This paper describes a systematic approach to select optimum stabilizer for the preparation of nano-crystalline suspensions of an active pharmaceutical ingredient (API). The stabilizer can be either a dispersant or a combination of dispersant and wetting agent. The proposed screening method is a quick and efficient way to investigate a large number of… CONTINUE READING