Engineering of PA-IIL lectin from Pseudomonas aeruginosa – Unravelling the role of the specificity loop for sugar preference

@article{Adam2007EngineeringOP,
  title={Engineering of PA-IIL lectin from Pseudomonas aeruginosa – Unravelling the role of the specificity loop for sugar preference},
  author={Jan Adam and Martina Johnson Pokorn{\'a} and Charles Sabin and Edward P Mitchell and Anne Imberty and Michaela Wimmerov{\'a}},
  journal={BMC Structural Biology},
  year={2007},
  volume={7},
  pages={36 - 36}
}
  • Jan Adam, Martina Johnson Pokorná, +3 authors Michaela Wimmerová
  • Published in BMC Structural Biology 2007
  • Medicine, Biology
  • BackgroundLectins are proteins of non-immune origin capable of binding saccharide structures with high specificity and affinity. Considering the high encoding capacity of oligosaccharides, this makes lectins important for adhesion and recognition. The present study is devoted to the PA-IIL lectin from Pseudomonas aeruginosa, an opportunistic human pathogen capable of causing lethal complications in cystic fibrosis patients. The lectin may play an important role in the process of virulence… CONTINUE READING

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