Engineering of Halomonas bluephagenesis for low cost production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from glucose.

@article{Ye2018EngineeringOH,
  title={Engineering of Halomonas bluephagenesis for low cost production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from glucose.},
  author={Jianwen Ye and Dingkai Hu and Xuemei Che and Xiaoran Jiang and Teng Li and Jinchun Chen and Haoqian M Zhang and Guoqiang Chen},
  journal={Metabolic engineering},
  year={2018},
  volume={47},
  pages={
          143-152
        }
}
Hyperproduction of 3-hydroxypropionate by Halomonas bluephagenesis
TLDR
Halomonas bluephagenesis shows the potential as a chassis for competitive bioproduction of various chemicals due to its ability to grow under an open, unsterile and continuous process and is reported to be a suitable chassis for hyperproduction of 3HP and P3HB3HP.
P(3HB-co-4HB) as high value polyhydroxyalkanoate: its development over recent decades and current advances
TLDR
A critical assessment and complete overview of the development and trend of P(3HB-co-4HB) research over the last few decades is provided, highlighting aspects from the microbial strain discovery to metabolic engineering and bioprocess cultivation strategies.
Poly(4-Hydroxybutyrate): Current State and Perspectives
TLDR
This review will comprehensively cover the historical evolution and the most recent publications on P4HB biosynthesis, material properties, and industrial and medical applications.
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References

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Microbial synthesis and properties of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) in Comamonas acidovorans.
  • Y. Saito, Y. Doi
  • Biology, Materials Science
    International journal of biological macromolecules
  • 1994
TLDR
The biodegradabilities of P(3HB-co-4HB) films were studied in aqueous solutions of extracellular polyhydroxybutyrate (PHB) depolymerase from Alcaligenes faecalis or of lipase from Rhizopus delemer, and the erosion rate of films by lipase increased with the 4HB fraction.
Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by metabolically engineered Escherichia coli strains.
TLDR
The 3HHx fraction in the copolymer could be increased by 3-fold when the Aeromonas hydrophila orf1 gene was coexpressed with the PHA biosynthesis genes.
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