Engineering neoglycoproteins with multiple O-glycans using repetitive pentapeptide glycosylation units

@article{Yoneda2001EngineeringNW,
  title={Engineering neoglycoproteins with multiple O-glycans using repetitive pentapeptide glycosylation units},
  author={Atsuko Yoneda and Masahiro Asada and Saori Yamamoto and Junko Oki and Yuko Oda and Keiko Ota and Yoko Ogi and Sachi Fujishima and Toru Imamura},
  journal={Glycoconjugate Journal},
  year={2001},
  volume={18},
  pages={291-299}
}
Controlled protein remodeling with O-linked glycans has been limited by our incomplete understanding of the process of glycosylation. Here we describe a secretable fibroblast growth factor (FGF) with multiple mucin-type O-glycans produced by introducing a minimum pentapeptide glycosylation unit in a decarepeat format at its N- or C-terminus. Expressed in… CONTINUE READING