Engineering intracellular biomineralization and biosensing by a magnetic protein.

  title={Engineering intracellular biomineralization and biosensing by a magnetic protein.},
  author={Yuri Matsumoto and Ritchie Chen and Polina Anikeeva and Alan Jasanoff},
  journal={Nature communications},
Remote measurement and manipulation of biological systems can be achieved using magnetic techniques, but a missing link is the availability of highly magnetic handles on cellular or molecular function. Here we address this need by using high-throughput genetic screening in yeast to select variants of the iron storage ferritin (Ft) that display enhanced iron accumulation under physiological conditions. Expression of Ft mutants selected from a library of 10(7) variants induces threefold greater… CONTINUE READING
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