Engineering challenges for brain tumor immunotherapy.


Malignant brain tumors represent one of the most devastating forms of cancer with abject survival rates that have not changed in the past 60years. This is partly because the brain is a critical organ, and poses unique anatomical, physiological, and immunological barriers. The unique interplay of these barriers also provides an opportunity for creative… (More)
DOI: 10.1016/j.addr.2017.06.006