Engineering cartilage tissues with the shape of human nasal alar by using chondrocyte macroaggregate--Experiment study in rabbit model.

Abstract

Despite of progresses in tissue engineering based on cell/scaffold strategy, uneven cell distribution as well as tissue formation in the scaffold, limited cell seeding efficiency and inflammatory reaction triggered by the degradation of scaffold remain problems to be resolved. In this study, we proposed a novel cell-macroaggregate cultivation system, and… (More)

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