Engineering biofilms for biocatalysis.

@article{Tsoligkas2011EngineeringBF,
  title={Engineering biofilms for biocatalysis.},
  author={Andreas N. Tsoligkas and Michael Winn and James L. Bowen and Tim W. Overton and Mark Simmons and Rebecca J M Goss},
  journal={Chembiochem : a European journal of chemical biology},
  year={2011},
  volume={12 9},
  pages={1391-5}
}
There is an increasing trend of using biotransformations in the fine chemicals industry, 2] however, a key problem facing this technology is the sensitivity of enzymes and even whole cells to extremes in pH, temperature and mechanical stress. Although there has been significant research into the use of extremophiles, fragility is still an issue. A solution might be found by employing biofilms, communities of cells protected by a secreted matrix; these are robust structures capable of… CONTINUE READING
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