Engineering approaches in siRNA delivery.


siRNAs are very potent drug molecules, able to silence genes involved in pathologies development. siRNAs have virtually an unlimited therapeutic potential, particularly for the treatment of inflammatory diseases. However, their use in clinical practice is limited because of their unfavorable properties to interact and not to degrade in physiological… (More)
DOI: 10.1016/j.ijpharm.2017.02.032


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@article{Barba2017EngineeringAI, title={Engineering approaches in siRNA delivery.}, author={Anna Angela Barba and Sara Cascone and Diego Caccavo and Gaetano Lamberti and Gianluca Chiarappa and Michela Abrami and Gabriele Grassi and Mario Grassi and Giovanna Tomaiuolo and Stefano Guido and Valerio B. Brucato and Francesco Carf{\`i} Pavia and Giulio Ghersi and Vincenzo La Carrubba and Roberto Andrea Abbiati and Davide Manca}, journal={International journal of pharmaceutics}, year={2017}, volume={525 2}, pages={343-358} }