Engineering a robust DNA split proximity circuit with minimized circuit leakage

Abstract

DNA circuit is a versatile and highly-programmable toolbox which can potentially be used for the autonomous sensing of dynamic events, such as biomolecular interactions. However, the experimental implementation of in silico circuit designs has been hindered by the problem of circuit leakage. Here, we systematically analyzed the sources and characteristics… (More)
DOI: 10.1093/nar/gkw447

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Cite this paper

@inproceedings{Ang2016EngineeringAR, title={Engineering a robust DNA split proximity circuit with minimized circuit leakage}, author={Yan Shan Ang and Rachel Tong and L. L. L. Yung}, booktitle={Nucleic acids research}, year={2016} }