Engineering RNA for targeted siRNA delivery and medical application.

@article{Guo2010EngineeringRF,
  title={Engineering RNA for targeted siRNA delivery and medical application.},
  author={Peixuan Guo and Oana Coban and Nicholas M Snead and Joe Trebley and Steve Hoeprich and Songchuan Guo and Yi Shu},
  journal={Advanced drug delivery reviews},
  year={2010},
  volume={62 6},
  pages={650-66}
}
RNA engineering for nanotechnology and medical applications is an exciting emerging research field. RNA has intrinsically defined features on the nanometre scale and is a particularly interesting candidate for such applications due to its amazing diversity, flexibility and versatility in structure and function. Specifically, the current use of siRNA to silence target genes involved in disease has generated much excitement in the scientific community. The intrinsic ability to sequence… CONTINUE READING
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Leontis, Tecto-RNA: One dimensional self-assembly through tertiary interactions

  • N.B.L. Jaeger
  • Angew. Chem. Int. Ed. Engl
  • 2000
Highly Influential
15 Excerpts

Szostak, In vitro selection of RNA molecules that bind specific ligands

  • J.W.A.D. Ellington
  • Nature
  • 1990
Highly Influential
4 Excerpts

Synthesis and characterization of a carbon nanotube-dendron series for efficient siRNA delivery

  • T.F.M.A. Herrero, K. T. Al-Jamal, +5 authors P.M.G. Scoles
  • J. Am. Chem. Soc
  • 2009
1 Excerpt

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