Engineering RNA for targeted siRNA delivery and medical application.

  title={Engineering RNA for targeted siRNA delivery and medical application.},
  author={Peixuan Guo and Oana Coban and Nicholas M Snead and Joe Trebley and Steve Hoeprich and Songchuan Guo and Yi Shu},
  journal={Advanced drug delivery reviews},
  volume={62 6},
RNA engineering for nanotechnology and medical applications is an exciting emerging research field. RNA has intrinsically defined features on the nanometre scale and is a particularly interesting candidate for such applications due to its amazing diversity, flexibility and versatility in structure and function. Specifically, the current use of siRNA to silence target genes involved in disease has generated much excitement in the scientific community. The intrinsic ability to sequence… CONTINUE READING
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