Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds

@inproceedings{Rodriguez2014EngineeringEC,
  title={Engineering Escherichia coli to overproduce aromatic amino acids and derived compounds},
  author={Alberto Rodriguez and Juan A Martnez and Noem Flores and Adelfo Escalante and Guillermo Gosset and Francisco G Bol{\'i}var},
  booktitle={Microbial cell factories},
  year={2014}
}
The production of aromatic amino acids using fermentation processes with recombinant microorganisms can be an advantageous approach to reach their global demands. In addition, a large array of compounds with alimentary and pharmaceutical applications can potentially be synthesized from intermediates of this metabolic pathway. However, contrary to other amino acids and primary metabolites, the artificial channelling of building blocks from central metabolism towards the aromatic amino acid… CONTINUE READING