Engineering Escherichia coli for selective geraniol production with minimized endogenous dehydrogenation.

@article{Zhou2014EngineeringEC,
  title={Engineering Escherichia coli for selective geraniol production with minimized endogenous dehydrogenation.},
  author={Jia Zhou and Chonglong Wang and Sang-Hwal Yoon and Hui-Jeong Jang and Eui-Sung Choi and Seon-Won Kim},
  journal={Journal of biotechnology},
  year={2014},
  volume={169},
  pages={
          42-50
        }
}
Geraniol, a monoterpene alcohol, has versatile applications in the fragrance industry, pharmacy and agrochemistry. Moreover, geraniol could be an ideal gasoline alternative. In this study, recombinant overexpression of geranyl diphosphate synthase and the bottom portion of a foreign mevalonate pathway in Escherichia coli MG1655 produced 13.3mg/L of geraniol. Introduction of Ocimum basilicum geraniol synthase increased geraniol production to 105.2mg/L. However, geraniol production encountered a… CONTINUE READING

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