Engineered spatial patterns of FGF-2 immobilized on fibrin direct cell organization.

@article{Campbell2005EngineeredSP,
  title={Engineered spatial patterns of FGF-2 immobilized on fibrin direct cell organization.},
  author={Phil G. Campbell and Eric D. Miller and Gregory W. Fisher and L. M. Walker and Lee E. Weiss},
  journal={Biomaterials},
  year={2005},
  volume={26 33},
  pages={6762-70}
}
The purpose of this study was to initiate the exploration of cell behavioral responses to inkjet printed spatial patterns of hormones biologically immobilized on biomimetic substrates. This approach was investigated using the example of preosteoblastic cell response in vitro to fibroblast growth factor-2 (FGF-2) printed on fibrin films. Concentration modulated patterns of FGF-2, including continuous concentration gradients, were created by overprinting dilute FGF-2 bioinks with a custom inkjet… CONTINUE READING

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