Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae

Abstract

Susceptibility to Plasmodium infection in Anopheles gambiae has been proposed to result from naturally occurring polymorphisms that alter the strength of endogenous innate defenses. Despite the fact that some of these mutations are known to introduce non-synonymous substitutions in coding sequences, these mutations have largely been used to rationalize… (More)
DOI: 10.1186/1756-3305-7-287

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@inproceedings{Brenton2014EngineeredSN, title={Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae}, author={Ashley A. Brenton and Lattha Souvannaseng and Kong Man Cheung and Michael Anishchenko and Aaron C Brault and Shirley Luckhart}, booktitle={Parasites & Vectors}, year={2014} }