Engineered nanoscaled polyplex gene delivery systems.

Abstract

Improving the transfection efficiencies of nonviral gene delivery requires properly engineered nanoscaled delivery carriers that can overcome the multiple barriers associated with the delivery of oligonucleotides from the site of administration to the nucleus or cytoplasm of the target cell. This article reviews the current advantages and limitation of… (More)
DOI: 10.1021/mp900033j

Topics

9 Figures and Tables

Cite this paper

@article{Fernandez2009EngineeredNP, title={Engineered nanoscaled polyplex gene delivery systems.}, author={Christian Fernandez and Kevin G. Rice}, journal={Molecular pharmaceutics}, year={2009}, volume={6 5}, pages={1277-89} }