Engineered multifunctional RGD-gold nanoparticles for the detection of tumour-specific alpha(v)beta(3) expression: chemical characterisation and ecotoxicological risk assessment.

Abstract

Radiolabelled nanoparticles conjugated to peptides that target specific molecules can be used as agents for diagnosis. For example, technetium-99m-labelled gold nanoparticles conjugated to the cyclic [Arg-Gly-Asp-Phe-Lys(Cys)] (c[RGDfK(C)]) peptide are used for the molecular imaging of tumour-specific alpha(epsilon)beta(3) expression. Gold nanoparticles… (More)

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Cite this paper

@article{MoralesAvila2012EngineeredMR, title={Engineered multifunctional RGD-gold nanoparticles for the detection of tumour-specific alpha(v)beta(3) expression: chemical characterisation and ecotoxicological risk assessment.}, author={Enrique Morales-Avila and Guillermina Ferro-Flores and Blanca Eli Ocampo-Garc{\'i}a and Leobardo Manuel G{\'o}mez-Oliv{\'a}n}, journal={Journal of biomedical nanotechnology}, year={2012}, volume={8 6}, pages={991-9} }