Engineered gene circuits

@article{Hasty2002EngineeredGC,
  title={Engineered gene circuits},
  author={Jeff Hasty and David McMillen and James J. Collins},
  journal={Nature},
  year={2002},
  volume={420},
  pages={224-230}
}
A central focus of postgenomic research will be to understand how cellular phenomena arise from the connectivity of genes and proteins. This connectivity generates molecular network diagrams that resemble complex electrical circuits, and a systematic understanding will require the development of a mathematical framework for describing the circuitry. From an engineering perspective, the natural path towards such a framework is the construction and analysis of the underlying submodules that… CONTINUE READING
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