Engineered Saccharomyces cerevisiae strain BioS-OS1/2, for the detection of oxidative stress.

@article{Jayaraman2005EngineeredSC,
  title={Engineered Saccharomyces cerevisiae strain BioS-OS1/2, for the detection of oxidative stress.},
  author={Muralidharan Jayaraman and Venkat Radhika and Mikhil N. Bamne and R Alexander Ramos and Rita Briggs and Danny N. Dhanasekaran},
  journal={Biotechnology progress},
  year={2005},
  volume={21 5},
  pages={
          1373-9
        }
}
One of the major stress factors during space and high-altitude flight is the oxidative damage caused by the release of reactive oxygen intermediates (ROIs) in human tissues. ROIs are released in response to several stress factors including radiation in space. Since ROIs contribute to several pathological conditions, there has been a great interest in developing a biosensor that can monitor the impact of ROIs on biological systems. Toward this goal, we sought to engineer a yeast stain that can… CONTINUE READING