Engineered Flock House Virus for Targeted Gene Suppression Through RNAi in Fruit Flies (Drosophila melanogaster) in Vitro and in Vivo

@inproceedings{Taning2018EngineeredFH,
  title={Engineered Flock House Virus for Targeted Gene Suppression Through RNAi in Fruit Flies (Drosophila melanogaster) in Vitro and in Vivo},
  author={Clauvis Nji Tizi Taning and Olivier Christiaens and Xiuxia Li and Luc Swevers and Hans F Casteels and Martine Maes and Guy Smagghe},
  booktitle={Front. Physiol.},
  year={2018}
}
RNA interference (RNAi) is a powerful tool to study functional genomics in insects and the potential of using RNAi to suppress crop pests has made outstanding progress. However, the delivery of dsRNA is a challenging step in the development of RNAi bioassays. In this study, we investigated the ability of engineered Flock House virus (FHV) to induce targeted gene suppression through RNAi under in vitro and in vivo condition. As proxy for fruit flies of agricultural importance, we worked with S2… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 83 REFERENCES

Caenorhabditis elegans. Nature 391:806

P. D. Friesen, R. R. Rueckert
  • 1981
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Ingested RNA

F. Zhu, J. Xu, R. Palli, J. Ferguson, S. R. Palli
  • 2011
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL