Enfuvirtide: first fusion inhibitor for treatment of HIV infection.

  title={Enfuvirtide: first fusion inhibitor for treatment of HIV infection.},
  author={M Christine Jamjian and Ian R. McNicholl},
  journal={American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists},
  volume={61 12},
PURPOSE The mechanism of action, pharmacokinetics, clinical efficacy, adverse effects, and availability of enfuvirtide are discussed. SUMMARY To date, 20 antiretrovirals have been approved by FDA for the treatment of HIV infection. The recent approval of enfuvirtide offers a new and fourth class of antiretroviral agents called fusion inhibitors… CONTINUE READING