Enflurane, halothane, and isoflurane inhibit removal of 5-hydroxytryptamine from the pulmonary circulation.

@article{Cook1982EnfluraneHA,
  title={Enflurane, halothane, and isoflurane inhibit removal of 5-hydroxytryptamine from the pulmonary circulation.},
  author={Daniel R Cook and Barbara Wendeborn Brandom},
  journal={Anesthesia and analgesia},
  year={1982},
  volume={61 8},
  pages={671-5}
}
We were interested in determining the effect of enflurane, halothane, and isoflurane on the uptake and removal of 5-hydroxytryptamine (5-HT) and phenylethylamine (PEA) from the lung. Isolated rabbit lungs were perfused in a recirculating system in vitro with 0.1 microM [14C]5-HT or 0.1 microM [14C]PEA in Krebs-Ringer solution. The rate of removal and percentage of removal of the bioamines were determined before and after either 1, 2, or 4 MAC multiples of the potent anesthetics. Because of… CONTINUE READING

From This Paper

Topics from this paper.
2 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…