Energy transduction in the F1 motor of ATP synthase

@article{Wang1998EnergyTI,
  title={Energy transduction in the F1 motor of ATP synthase},
  author={Hongyun Wang and George F. Oster},
  journal={Nature},
  year={1998},
  volume={396},
  pages={279-282}
}
ATP synthase is the universal enzyme that manufactures ATP from ADP and phosphate by using the energy derived from a transmembrane protonmotive gradient. It can also reverse itself and hydrolyse ATP to pump protons against an electrochemical gradient. ATP synthase carries out both its synthetic and hydrolytic cycles by a rotary mechanism. This has been confirmed in the direction of hydrolysis, after isolation of the soluble F1 portion of the protein and visualization of the actual rotation of… 
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Structure of a bacterial ATP synthase
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The architecture of the membrane region shows how the simple bacterial ATP synthase is able to perform the same core functions as the equivalent, but more complicated, mitochondrial complex, and reveals the path of transmembrane proton translocation.
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References

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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ATP-dependent, azide-sensitive rotation of the γ subunit relative to the α3β3 hexagonal ring of ATP synthase was observed with a single molecule imaging system. Thus, ATP synthase is a rotary motor…
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ATP-dependent, azide-sensitive rotation of the gamma subunit relative to the alpha3beta3 hexagonal ring of ATP synthase was observed with a single molecule imaging system. Thus, ATP synthase is a…
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