• DOI:10.1111/j.1742-4658.2007.05686.x
Corpus ID: 7748115

Energy metabolism in tumor cells

@article{MorenoSnchez2007EnergyMI,
  title={Energy metabolism in tumor cells},
  author={R. Moreno-S{\'a}nchez and S. Rodr{\'i}guez-Enr{\'i}quez and {\'A}. Mar{\'i}n-Hern{\'a}ndez and E. Saavedra},
  journal={The FEBS Journal},
  year={2007},
  volume={274}
}

• R. Moreno-Sánchez, S. Rodríguez-Enríquez, +1 author E. Saavedra
• Published 2007
• Biology, Medicine
• The FEBS Journal

In early studies on energy metabolism of tumor cells, it was proposed that the enhanced glycolysis was induced by a decreased oxidative phosphorylation. Since then it has been indiscriminately applied to all types of tumor cells that the ATP supply is mainly or only provided by glycolysis, without an appropriate experimental evaluation. In this review, the different genetic and biochemical mechanisms by which tumor cells achieve an enhanced glycolytic flux are analyzed. Furthermore, the… Expand