Energy metabolism, ion homeostasis, and cell damage in the brain.

@article{Katsura1994EnergyMI,
  title={Energy metabolism, ion homeostasis, and cell damage in the brain.},
  author={K. Katsura and T. Kristian and B. Siesj{\"o}},
  journal={Biochemical Society transactions},
  year={1994},
  volume={22 4},
  pages={
          991-6
        }
}
observed neither on metabolic deprivation nor on depolarization, but only after treatment with excitotoxins [7,9]. In related experiments (results not shown) using ‘T-m.r. to study flux through metabolic pathways, we observed quite different patterns between these various insults. NMDA caused rapidly decreased N-acetylaspartate and increased lactate, with slow decreases in pool sizes of amino acids [lo], in marked contrast to the changes caused by severe hypoxia [ l l ] or depolarization 
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