• Corpus ID: 173990666

Energy landscapes and dynamics of xylo-nucleic acids.

@article{Sharpe2019EnergyLA,
  title={Energy landscapes and dynamics of xylo-nucleic acids.},
  author={Daniel J. Sharpe and Konstantin Roeder and David J. Wales},
  journal={arXiv: Biological Physics},
  year={2019}
}
Artificial analogues of the natural nucleic acids have attracted recent interest as a diverse class of information storage molecules capable of self-replication. In the present study, we use the computational potential energy landscape framework to investigate the structural and dynamical properties of xylo- and deoxyxylo-nucleic acids (XyNA and dXyNA), which are derived from their respective RNA and DNA analogues by an inversion of configuration at a single chiral center in the sugar moiety of… 
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