Energy imbalance alters Ca2+ handling and excitability of POMC neurons

Abstract

Satiety-signaling, pro-opiomelanocortin (POMC)-expressing neurons in the arcuate nucleus of the hypothalamus play a pivotal role in the regulation of energy homeostasis. Recent studies reported altered mitochondrial dynamics and decreased mitochondria- endoplasmic reticulum contacts in POMC neurons during diet-induced obesity. Since mitochondria play a… (More)
DOI: 10.7554/eLife.25641

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Cite this paper

@inproceedings{Paeger2017EnergyIA, title={Energy imbalance alters Ca2+ handling and excitability of POMC neurons}, author={Lars Paeger and Andreas Pippow and Simon Hess and Moritz Paehler and Andreas Klein and Andreas Husch and Christophe Pouzat and Jens C. Br{\"u}ning and Peter Kloppenburg}, booktitle={eLife}, year={2017} }