Energy-converting hydrogenases: the link between H2 metabolism and energy conservation

@article{Schoelmerich2019EnergyconvertingHT,
  title={Energy-converting hydrogenases: the link between H2 metabolism and energy conservation},
  author={Marie Charlotte Schoelmerich and Volker M{\"u}ller},
  journal={Cellular and Molecular Life Sciences},
  year={2019},
  volume={77},
  pages={1461 - 1481}
}
The reversible interconversion of molecular hydrogen and protons is one of the most ancient microbial metabolic reactions and catalyzed by hydrogenases. A widespread yet largely enigmatic group comprises multisubunit [NiFe] hydrogenases, that directly couple H2 metabolism to the electrochemical ion gradient across the membranes of bacteria and of archaea. These complexes are collectively referred to as energy-converting hydrogenases (Ech), as they reversibly transform redox energy into… 
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