Energy barriers for HET-s prion forming domain amyloid formation.

@article{Sabat2009EnergyBF,
  title={Energy barriers for HET-s prion forming domain amyloid formation.},
  author={Raimon Sabat{\'e} and Virginia Castillo and Alba Espargar{\'o} and Sven J. Saupe and Salvador Ventura},
  journal={The FEBS journal},
  year={2009},
  volume={276 18},
  pages={5053-64}
}
The prion-forming domain comprising residues 218-289 of the fungal prion HET-s forms infectious amyloid fibrils at physiological pH. Because a high-resolution molecular model for the structure of these fibrils exists, it constitutes an attractive system with which to study the mechanism of amyloid assembly. Understanding aggregation under specific… CONTINUE READING