Energetics of Transport through the Nuclear Pore Complex.

@article{Ghavami2016EnergeticsOT,
  title={Energetics of Transport through the Nuclear Pore Complex.},
  author={Ali Ghavami and Erik van der Giessen and P. R. Onck},
  journal={PloS one},
  year={2016},
  volume={11 2},
  pages={e0148876}
}
Molecular transport across the nuclear envelope in eukaryotic cells is solely controlled by the nuclear pore complex (NPC). The NPC provides two types of nucleocytoplasmic transport: passive diffusion of small molecules and active chaperon-mediated translocation of large molecules. It has been shown that the interaction between intrinsically disordered proteins that line the central channel of the NPC and the transporting cargoes is the determining factor, but the exact mechanism of transport… CONTINUE READING
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