Energetics and partition of two cecropin-melittin hybrid peptides to model membranes of different composition.

@article{Bastos2008EnergeticsAP,
  title={Energetics and partition of two cecropin-melittin hybrid peptides to model membranes of different composition.},
  author={Margarida Bastos and Guangyue Bai and Paula Gomes and David Andreu and Erik Goormaghtigh and Manuel Prieto},
  journal={Biophysical journal},
  year={2008},
  volume={94 6},
  pages={
          2128-41
        }
}
The energetics and partition of two hybrid peptides of cecropin A and melittin (CA(1-8)M(1-18) and CA(1-7)M(2-9)) with liposomes of different composition were studied by time-resolved fluorescence spectroscopy, isothermal titration calorimetry, and surface plasmon resonance. The study was carried out with large unilamellar vesicles of three different lipid compositions: 1,2-dimyristoil-sn-glycero-3-phosphocholine (DMPC), 1,2-dimyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) (DMPG), and a 3:1… CONTINUE READING

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