Energetics and electrogenicity of the sarcoplasmic reticulum calcium pump.

@article{Hasselbach1983EnergeticsAE,
  title={Energetics and electrogenicity of the sarcoplasmic reticulum calcium pump.},
  author={Wilhelm Hasselbach and Hans Dr. Med. Oetliker},
  journal={Annual review of physiology},
  year={1983},
  volume={45},
  pages={
          325-39
        }
}
Activity of skeletal muscle is regulated by the free myoplasmic calcium concentration, [CaH], which varies from 5 . 10-8 M at rest to 5 . l(rf> M during activity. About 90% of activator Ca is contained in the terminal cisternae of the sarcoplasmic reticulum (SR), whence Ca is released by a still unknown mechanism. The SR occupies about 9% of muscle volume and has a surface area (S) of 2 m2 per gram muscle. Its internal [CaH] is in the order of 0.5-2 mM (Table 1). One activation-relaxation cycle… CONTINUE READING

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