Energetics and dynamics of constrained actin filament bundling.

  title={Energetics and dynamics of constrained actin filament bundling.},
  author={Le Yang and David Sept and Anders E. Carlsson},
  journal={Biophysical journal},
  volume={90 12},
The formation of filopodia-like bundles from a dendritic actin network has been observed to occur in vitro as a result of branching induced by Arp2/3 complex. We study both the energetics and dynamics of actin filament bundling in such a network to evaluate their relative importance in bundle formation processes. Our model considers two semiflexible actin filaments fixed at one end and free at the other, described using a normal-mode approximation. This model is studied by both Brownian… CONTINUE READING