Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream 1

@inproceedings{Martinez2019EnemasWM,
  title={Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream
1

},
  author={Carlos Augusto Real Martinez and F{\'a}bio Guilherme Campos and Danilo Toshio Kanno and Eli Cristiano Meneses and Gabrielle Maira Matijascic and Eduardo Felipe Kim Goto and Jos{\'e} Aires Pereira},
  booktitle={Acta cirurgica brasileira},
  year={2019}
}
PURPOSE To evaluate the inflammatory reaction and measure the content of mucins, in the colonic mucosa without fecal stream submit to intervention with mesalazine. METHODS Twenty-four rats were submitted to a left colostomy and a distal mucous fistula and divided into two groups according to euthanasia to be performed two or four weeks. Each group was divided into two subgroups according daily application of enemas containing saline or mesalazine at 1.0 g/kg/day. Colitis was diagnosed by… CONTINUE READING

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