Enduring Value of Thiopurines for Inflammatory Bowel Disease Therapy

Prior to the advent of the use of infliximab and other biologics for the treatment of ulcerative colitis, the immunosuppressive drugs, azathioprine (AZA) and 6-mercaptopurine (6-MP), provided long-term remissions beyond that accomplished by sulfasalazine, 5-aminosalicylates, and corticosteroids [1]. The response to these two thiopurines was neither marked… CONTINUE READING