Endurance interval training in obese mice reduces muscle inflammation and macrophage content independently of weight loss

@inproceedings{Samaan2014EnduranceIT,
  title={Endurance interval training in obese mice reduces muscle inflammation and macrophage content independently of weight loss},
  author={M Constantine Samaan and Katarina Marcinko and Sarah R. Sikkema and Morgan D. Fullerton and Tahereh Ziafazeli and Mohammad Imran Khan and Gregory R Steinberg},
  booktitle={Physiological reports},
  year={2014}
}
Obesity is associated with chronic low-grade inflammation that involves infiltration of macrophages into metabolic organs such as skeletal muscle. Exercise enhances skeletal muscle insulin sensitivity independently of weight loss; but its role in regulating muscle inflammation is not fully understood. We hypothesized that exercise training would inhibit skeletal muscle inflammation and alter macrophage infiltration into muscle independently of weight loss. Wild type C57BL/6 male mice were fed a… CONTINUE READING
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