Endurance exercise differentially stimulates heart and axial muscle development in zebrafish (Danio rerio).

@article{Meulen2006EnduranceED,
  title={Endurance exercise differentially stimulates heart and axial muscle development in zebrafish (Danio rerio).},
  author={Talitha van der Meulen and Hyman Schipper and Jos G M van den Boogaart and Mark O. Huising and Sander Kranenbarg and Johan L van Leeuwen},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2006},
  volume={291 4},
  pages={R1040-8}
}
Mechanical load is an important factor in the differentiation of cells and tissues. To investigate the effects of increased mechanical load on development of muscle and bone, zebrafish were subjected to endurance swim training for 6 h/day for 10 wk starting at 14 days after fertilization. During the first 3 wk of training, trained fish showed transiently increased growth compared with untrained (control) fish. Increased expression of proliferating cell nuclear antigen suggests that this growth… CONTINUE READING

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