Endpoints and cutpoints in head and neck oncology trials: methodical background, challenges, current practice and perspectives

Abstract

This article reviews the methodical and statistical basics of designing a trial, with a special focus on the process of defining and choosing endpoints and cutpoints as the foundations of clinical research, and ultimately that of evidence-based medicine. There has been a significant progress in the treatment of head and neck cancer in the past few decades… (More)
DOI: 10.1007/s00405-014-3472-x

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