Endplate current fluctuations reveal only one channel type at frog neuromuscular junction

@article{Dionne1977EndplateCF,
  title={Endplate current fluctuations reveal only one channel type at frog neuromuscular junction},
  author={Vincent E. Dionne and Robert Louis Ruff},
  journal={Nature},
  year={1977},
  volume={266},
  pages={263-265}
}
SIGNAL transduction between nerve and muscle is mediated by a chemical process at the neuromuscular junction. In the nerve ending electrical activity causes the release of acetylcholine (ACh) into the synaptic cleft separating the nerve and muscle cells. ACh can bind to specific chemical receptors in the postjunctional muscle membrane; these receptors control a gating mechanism that can increase membrane conductance locally. Normal nervous activity triggers an action potential and contraction… CONTINUE READING
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