Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

@article{Goyal2016EndovascularTA,
  title={Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials},
  author={M. Goyal and B. Menon and W. V. Zwam and D. Dippel and Hermes collaborators},
  journal={The Lancet},
  year={2016},
  volume={387},
  pages={1723-1731}
}
BACKGROUND In 2015, five randomised trials showed efficacy of endovascular thrombectomy over standard medical care in patients with acute ischaemic stroke caused by occlusion of arteries of the proximal anterior circulation. In this meta-analysis we, the trial investigators, aimed to pool individual patient data from these trials to address remaining questions about whether the therapy is efficacious across the diverse populations included. METHODS We formed the HERMES collaboration to pool… Expand
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Paper Mentions

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References

SHOWING 1-10 OF 33 REFERENCES
Thrombectomy within 8 hours after symptom onset in ischemic stroke.
  • 2,815
  • PDF
A systematic review and meta‐analysis of randomized controlled trials of endovascular thrombectomy compared with best medical treatment for acute ischemic stroke
  • 78
Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke.
  • 2,997
  • PDF
Endovascular vs medical management of acute ischemic stroke
  • 60
A randomized trial of intraarterial treatment for acute ischemic stroke.
  • 3,882
  • PDF
Endovascular therapy for ischemic stroke with perfusion-imaging selection.
  • 3,355
  • PDF
...
1
2
3
4
...